A supplier will quote a base cost and a first-order cost which accounts for tooling. Tooling refers to the cutting dies and printing plates that are custom made to print and cut your item.
Sometimes, a supplier may have to slightly adjust your specs to optimize for their machine capabilities.
If they do have to change the specifications, they will likely send a message with their quote, but it's a good practice to double check the specifications before accepting a quote.
Tip: To see the history of quotes and quote requests for each item, click on the item in your Items view and scroll to Quote requests.